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| Antigenic |
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antigenic/emboss Kolaskar and Tongaonkar Jameson and Wolf
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| Clustered |
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systers
Proclust
protonet Clustr
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| Various |
- Pathways: pathway-guide
- in contrast to nucleotide composition in genomes, amino-acid comp. in proteomes is similar across kingdoms. aa-distribution as in Rost "Did evolution leap.." 2002.
| Motifs |
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| 3D analysis |
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| Gene ontology |
- Ontoexpress (Web-based, Java GUI, all GO-cat, 4 stat tests, needs login, very slow): automatically translates lists of differentially regulated genes into functional profiles characterizing the impact of the condition studied.
- GoMiner (stand-alone windows, organism specific IDs, total genome as reference set for Pvalue)
- Genemerge (-) (web and stand-alone, abstracts to lowest level, one cat at a time, KEGG for fly and yeast, needs refernce upload, hypergeometric - uses FBgn, with GeneNameconverter)
- Funcassociate (web, CG, abstracts to lowest level)
- GOstat user can choose between 2 stat tests, total genome as ref for Pvalue, understands all from fb
- GOToolBox (web-based, organism specific ids, choice of 3 tests, total genome as ref for Pvalue) FBgn, CG
- FatiGO (web-based, organism specific ids, one GO cat at a time, total genome as ref for Pvalue) FBgn, CG - percentage
- eGOn needs login, allows user to collapse and expand nodes
- GOTM needs login, allows the user to collapse and expand nodes, understands CG numbers, but is not the optimal visualizatioor p
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| Expression |
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E-northern
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| Alignment |
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| Fibrillar stuff |
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coil matcher
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| Interaction databases |
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| Evaluate-confirm structure |
- visualization: pymol vmd
- Evaluate structure model using Prosa2003, Verify3D, ProQ and/or MaxSub
- surface projection of conservation: consurf, rate4site
- DALI- checks if fold correct, similarity by pseudo-energy Z-score
- biotech procheck- checks stereochemistry
- Errat Verify3D anolea- check spatial features compiled from high resolution protein structures
- hubmed
- Endeavour for the computational prioritisation of `test genes', based on a set of `training genes'.
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